Mirror Life Is a Scientific Fantasy Leading to a Dangerous Reality − a Synthetic Biologist Explains How Mirror Bacteria Could Conquer Life on Earth

February 11, 2025| Source: The Conversation | by Kate Adamala

Most major biological molecules, including all proteins, DNA and RNA, point in one direction or another. In other words, they are chiral, or handed. Like how your left glove fits only your left hand and your right glove your right hand, chiral molecules can interact only with other molecules of compatible handedness.

Two chiralities are possible: left and right, formally called L for the Latin laevus and D for dexter. All life on Earth uses L proteins and D sugars. Even Archaea, a large group of microorganisms with unusual chemical compositions, stick to the program on the handedness of the main molecules they use.

For a long time, scientists have been speculating about making biopolymers that would mirror compounds in nature but in the opposite orientation – namely, compounds made of D proteins and L sugars. Recent years have seen some promising advancements, including enzymes that can make mirror RNAs and mirror DNAs.