Even Low Levels of Traffic Air Pollution Can Damage the Liver, New Study Shows
February 03, 2025 | Source: U.S. Right to Know | by
Long-term exposure to even small amounts of air pollution from vehicles promotes abnormal changes in the liver—potentially increasing the risk of fatty liver disease, according to new research in mice.
Mice exposed to fine particulate matter (PM2.5, or tiny pollutant particles of 2.5 micrometers or less) for 12 weeks showed inflammation in the liver, more fat buildup, and changes in certain fat-related molecules, according to the study, published Jan. 27 [2025] in the Journal of Environmental Sciences. The researchers also found an increase in liver immune cells (macrophages), suggesting that the liver had been damaged and was trying to repair itself.
“Previous research has shown that exposure to heavily polluted air is associated with liver disorders, however this study reveals even low levels can cause harm. It suggests there is no safe level of exposure to traffic-derived air pollution,” says Professor Hui Chen from the University of Technology Sydney (UTS), who co-authored the study with international expert Professor Jacob George, director of the Storr Liver Centre.